Hormone Optimization Panel

Hormone testing that tells the whole story

Most hormone tests capture a single moment — one blood draw, one number. But hormones rise and fall throughout the day, get metabolized into dozens of downstream compounds, and respond constantly to your environment. A snapshot misses what matters most.

The Hormone Optimization Panel uses advanced urinary and salivary analysis to capture your hormones across the full day, trace them through their metabolic pathways, and reveal the environmental factors shaping how you feel.

What it measures

• Sex hormones and metabolites — estradiol, estrone, estriol, testosterone, DHEA, progesterone, and the downstream metabolites that reveal how your body processes them
• Cortisol rhythm — free cortisol and cortisone measured across the day, plus a salivary Cortisol Awakening Response
• Melatonin patterns — diurnal measurements for sleep and circadian insight
• Endocrine-disrupting chemicals — BPA, phthalates, parabens, glyphosate, atrazine, triclosan, and perchlorate
• Oxidative stress and bone turnover — 8-OHdG, plus DPD and PYD crosslinks

Who it's for

People wanting clarity around fatigue, mood shifts, sleep disruption, stubborn weight changes, low libido, irregular cycles, perimenopause and menopause shifts, hot flashes, hair or skin changes, bone health concerns, or long-term environmental chemical exposure.

Why this panel is different

A standard hormone blood test asks: Is this number in range? This panel asks: How is your body producing, metabolizing, and clearing your hormones — and what's influencing the process? Two people with identical estrogen levels can have entirely different hormone health, depending on which metabolic pathway their body favors.

How it works

Your kit ships to your home. You collect simple urine and saliva samples across a single day — no blood draw required — then return everything with the prepaid shipping label. Results arrive in 2–4 weeks through your secure DeNovo Longevity portal.

This panel is intended solely for informational and wellness purposes to help inform lifestyle choices. It is not intended for diagnostic purposes and is not a substitute for medical advice. Please consult a licensed healthcare practitioner for any questions regarding diagnosis, prevention, or treatment of any disease or health condition.