DeNovo Longevity
Body Recomposition Blueprint
Body Recomposition Blueprint
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Reset your metabolism. Reclaim your health. Transform your body.
The DeNovo Weight & Body Recomposition Blueprint is a complete program — combining physician-prescribed compounded medications, personalized lab testing, custom supplements, and the coaching infrastructure you need to build lasting metabolic health. Because weight loss achieved through optimization, not deprivation, is weight that stays off.
Choose the tier that matches the depth of support you want — Foundations, Advanced, or Elite.
What Every Program Includes
- 3-month supply of physician-prescribed, compounded medications (varies by tier)
- Personalized lab testing to inform your protocol (varies by tier)
- Custom supplements to support weight loss and metabolic health
- Nutrition tracking app for macro and micronutrient insights
- Fitness app with personalized workout programming
- Weekly group coaching sessions to help you stay on track and meet your goals
All medications, injection supplies, lab testing, and shipping included.
Choose Your Protocol
Foundations Recomposition Package
Semaglutide + Nutrigenomic Testing + Functional Health Labs
The entry point — pairing a compounded GLP-1 injectable with the foundational testing you need to personalize your approach. Nutrigenomic testing reveals how your genes influence metabolism, nutrient processing, and weight regulation, while Functional Health Labs establish a clear baseline of how your body is actually functioning today.
Includes everything in the program above.
Advanced Recomposition Package
Tirzepatide + Sermorelin + Nutrigenomic Testing + Advanced Cardiometabolic Labs
Upgrades to dual-agonist tirzepatide and adds Sermorelin to support natural growth hormone production — pairing broader metabolic signaling with the regenerative hormonal layer that drives lean muscle preservation, sleep quality, and recovery during weight loss. Advanced Cardiometabolic Labs go deeper than standard panels to reveal the underlying drivers of metabolic dysfunction, cardiovascular risk, and inflammation.
Includes everything in the program above, plus a 1:1 Health & Performance Optimization Consult to translate your lab results and genetics into a personalized plan that accounts for your lifestyle, preferences, fitness level, and goals.
Elite Recomposition Package
Tirzepatide + Sermorelin + Nutrigenomic Testing + Advanced Cardiometabolic Panel + Cellular Nutrition Panel
DeNovo's most comprehensive recomposition protocol — adding Cellular Nutrition Panel testing to assess the micronutrient status inside your cells, where metabolism actually happens. This is the definitive choice for adults who want full body recomposition guided by the deepest diagnostic picture available.
Includes everything in the program above, plus monthly 1:1 Health & Performance Optimization Consults to track progress, interpret evolving data, adjust your plan as needed, and keep every layer of your protocol moving in the right direction.
The Compounds and What They Do
Semaglutide — GLP-1 Receptor Agonist
GLP-1 (glucagon-like peptide-1) is a hormone your body naturally produces in response to eating. It signals the brain that you are full, slows gastric emptying, regulates blood sugar, reduces inflammation, and improves insulin sensitivity. In people struggling with weight, this signaling is often blunted. GLP-1 receptor agonist therapy restores and amplifies these signals.
Potential benefits: reduced appetite, improved blood sugar regulation, enhanced insulin sensitivity, reduced inflammation, and the metabolic environment needed for sustainable weight loss.
Tirzepatide — Dual GLP-1 & GIP Agonist
Tirzepatide activates both the GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) pathways simultaneously, delivering significantly broader metabolic and anti-inflammatory signaling than GLP-1 alone. Emerging research also points to neuroprotective and cognitive benefits, reinforcing the connection between metabolic health and brain health.
Potential benefits: stronger appetite regulation, improved insulin sensitivity, optimized lipid metabolism, reduced inflammation, and neuroprotective support.
Sermorelin — Natural Growth Hormone Support
Sermorelin is a peptide that stimulates your pituitary gland to naturally produce and release more of your own growth hormone. Unlike synthetic growth hormone, Sermorelin works with your body's own regulatory systems. Growth hormone plays a central role in fat metabolism, lean muscle preservation, cellular repair, sleep quality, and overall vitality.
Potential benefits: lean muscle preservation during weight loss, enhanced fat metabolism, deeper restorative sleep, improved recovery, and the hormonal environment that supports vitality.
The Lab Testing and What It Reveals
Nutrigenomic Testing
Nutrigenomic testing analyzes your genetic variants to reveal how your body processes nutrients, responds to different foods and macronutrient ratios, regulates inflammation, and handles detoxification. Because your genes shape how you respond to nutrition and lifestyle interventions, this testing makes it possible to personalize your protocol based on your actual biology rather than generic recommendations.
What it informs: macronutrient strategy, micronutrient needs, supplementation priorities, and the lifestyle interventions most likely to work for your unique genetic profile.
Functional Health Labs
Functional Health Labs establish a comprehensive baseline of how your body is actually functioning — looking beyond standard reference ranges to identify the subtle imbalances that drive weight gain, fatigue, and metabolic dysfunction. This is the foundational picture every serious weight loss protocol should start with.
What it informs: baseline metabolic health, inflammation status, nutrient sufficiency, and the early signals that guide protocol decisions.
Advanced Cardiometabolic Labs
Advanced Cardiometabolic Labs go beyond standard cholesterol panels to assess the actual drivers of cardiovascular and metabolic risk — including insulin resistance, advanced lipid particle analysis, inflammatory markers, and the biomarkers most closely tied to long-term metabolic health.
What it informs: insulin sensitivity, cardiovascular risk, inflammatory burden, and the metabolic levers most worth targeting in your protocol.
Cellular Nutrition Panel
A Cellular Nutrition Panel measures the micronutrient status inside your cells — where metabolism actually happens — rather than just what's circulating in your blood. This level of testing reveals functional deficiencies that standard blood work misses, identifying where your cellular machinery is under-supplied and limiting your results.
What it informs: intracellular nutrient status, mitochondrial support needs, targeted supplementation, and the cellular-level optimization that drives the deepest results.
Why This Matters
Excess weight is rarely just a willpower problem. It is a metabolic problem — driven by hormonal dysregulation, chronic inflammation, insulin resistance, and a hunger and satiety system pushed deeply out of balance. Addressing it well requires more than medication. It requires understanding your biology — your genes, your biomarkers, your cellular nutrient status — and building a protocol around what your body actually needs.
More Than Medication
Medication opens the door. Lab testing tells you what's behind it. Coaching and personalized guidance help you walk through and stay through. That's why every Weight & Body Recomposition Blueprint package combines biochemistry with diagnostics and behavior — pairing physician-prescribed protocols with the testing, tools, coaching, and personalized guidance that turn short-term results into lasting change.
What's Included
All compounded medications, injection supplies, lab testing, and shipping included. No hidden costs.
A brief medical intake is required prior to prescribing. A $20 physician consultation fee will be billed directly by the prescribing physician and is not included in the package price.
Individual results may vary. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Compounded medications are not FDA-approved.
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